Detalhe da pesquisa
1.
PIKFYVE inhibition mitigates disease in models of diverse forms of ALS.
Cell
; 186(4): 786-802.e28, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36754049
2.
Ferrying wingless across the synaptic cleft.
Cell
; 139(2): 229-31, 2009 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-19837027
3.
The M1311V variant of ATP7A is associated with impaired trafficking and copper homeostasis in models of motor neuron disease.
Neurobiol Dis
; 149: 105228, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33359139
4.
Increased Cardiac Arrhythmogenesis Associated With Gap Junction Remodeling With Upregulation of RNA-Binding Protein FXR1.
Circulation
; 137(6): 605-618, 2018 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29101288
5.
PPAR gamma activation is neuroprotective in a Drosophila model of ALS based on TDP-43.
Hum Mol Genet
; 24(6): 1741-54, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25432537
6.
PABPN1 suppresses TDP-43 toxicity in ALS disease models.
Hum Mol Genet
; 24(18): 5154-73, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26130692
7.
Fragile X protein mitigates TDP-43 toxicity by remodeling RNA granules and restoring translation.
Hum Mol Genet
; 24(24): 6886-98, 2015 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26385636
8.
-2019 PLOS Genetics Research Prize: Fruit fly school - language and dialects for communicating a threat.
PLoS Genet
; 15(9): e1008381, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31513586
9.
Futsch/MAP1B mRNA is a translational target of TDP-43 and is neuroprotective in a Drosophila model of amyotrophic lateral sclerosis.
J Neurosci
; 34(48): 15962-74, 2014 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25429138
10.
A Helping Hand: RNA-Binding Proteins Guide Gene-Binding Choices by Cohesin Complexes.
PLoS Genet
; 12(11): e1006419, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27855157
11.
Wild-type and A315T mutant TDP-43 exert differential neurotoxicity in a Drosophila model of ALS.
Hum Mol Genet
; 20(12): 2308-21, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21441568
12.
Desmoplakin and talin2 are novel mRNA targets of fragile X-related protein-1 in cardiac muscle.
Circ Res
; 109(3): 262-71, 2011 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21659647
13.
Modelling TDP-43 proteinopathy in Drosophila uncovers shared and neuron-specific targets across ALS and FTD relevant circuits.
Acta Neuropathol Commun
; 11(1): 168, 2023 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37864255
14.
Fragile X protein controls neural stem cell proliferation in the Drosophila brain.
Hum Mol Genet
; 19(15): 3068-79, 2010 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20504994
15.
The cell adhesion molecule Roughest depends on beta(Heavy)-spectrin during eye morphogenesis in Drosophila.
J Cell Sci
; 123(Pt 2): 277-85, 2010 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20048344
16.
Dysregulation of Translation in TDP-43 Proteinopathies: Deficits in the RNA Supply Chain and Local Protein Production.
Front Neurosci
; 16: 840357, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35321094
17.
TDP-43 Proteinopathy Causes Broad Metabolic Alterations including TCA Cycle Intermediates and Dopamine Levels in Drosophila Models of ALS.
Metabolites
; 12(2)2022 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35208176
18.
Heads-up: new roles for the fragile X mental retardation protein in neural stem and progenitor cells.
Genesis
; 49(6): 424-40, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21404421
19.
Measuring Glucose Uptake in Drosophila Models of TDP-43 Proteinopathy.
J Vis Exp
; (174)2021 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34424253
20.
TDP-43 proteinopathy alters the ribosome association of multiple mRNAs including the glypican Dally-like protein (Dlp)/GPC6.
Acta Neuropathol Commun
; 9(1): 52, 2021 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33762006